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  George W. Bush’s failures may have set off a tectonic shift in US presidential politics, commencing a Democratic Party reign  
 
 
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   Alan Lupo was many things — among them, the best metro columnist Boston may ever see   
 
 
 
  A rift between science and activism is undermining progress in the fight against AIDS  
 
 
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   Steering a suddenly lost GOP ship,   
 
 
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  Self-declared financial ignoramus revels in the fact that investing ‘geniuses’ probably know less than  she  does